THE GEOTOX PACKAGE: OPEN-SOURCE SOFTWARE FOR CONNECTING SPATIOTEMPORAL EXPOSURE TO INDIVIDUAL AND POPULATION-LEVEL RISK

The GeoTox Package: open-source software for connecting spatiotemporal exposure to individual and population-level risk

Abstract Background Comprehensive environmental risk characterization, encompassing physical, chemical, social, ecological, and lifestyle stressors, necessitates innovative approaches to 141 handle the escalating complexity.This is especially true when considering individual and population-level diversity, where the myriad combinations of real-worl

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Substrate-induced unfolding of protein disulfide isomerase displaces the cholera toxin A1 subunit from its holotoxin.

To Soccer - Shoes Outdoor - Senior generate a cytopathic effect, the catalytic A1 subunit of cholera toxin (CT) must be separated from the rest of the toxin.Protein disulfide isomerase (PDI) is thought to mediate CT disassembly by acting as a redox-driven chaperone that actively unfolds the CTA1 subunit.Here, we show that PDI itself unfolds upon co

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Development of anti-foulant ultraviolet-assisted polyvinyl alcohol layer on the polysulfone-based nanohybrid membrane for industrial rubber wastewater decontamination

Introduction: Membrane fouling has been reported to be one of the bottlenecks of membrane technologies for wastewater treatment.To mitigate its negative impacts, we fabricated polysulfone membrane (PSf) composites made of silica (SiO2) and graphene oxide (GO) nanoparticles that modified with ultraviolet (UV)-assisted polyvinyl alcohol layer on the

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